The　moving　particle　semi-implicit　(MPS)　method　is　a　fully　Lagrangian　meshless　method　developed　for　incompressible　viscous　flow.　A　particle　interaction　model　of　moving　boundary　was　established　for　studying　the　flow　with　moving　component.　The　simulation　results　of　concentric　shaft　rotation　were　in　good　agreement　with　the　analytic　solution,　and　an　example　of　cross　agitator　rotating　in　water　was　simulated,　which　well　described　the　physic　process.　The　new　model　expands　the　applications　of　MPS　method　and　introduces　a　new　way　in　studying　on　this　kind　of　fluid　machinery.