The　purpose　of　this　study　was　to　investigate　the　effects　of　heat-treatment　conditions　on　the　microstructure　and　properties　of　a　novel　lithium　disilicate　glass-ceramic　for　dental　restorative　applications.　The　parent　glass　derived　from　SiO2-Li2O-K2O-Al2O3-ZrO2-P2O　system　was　melted　and　subjected　to　different　heat-treatment　conditions.　After　respective　heat-treatments,　the　crystalline　phase　composition　and　microstructures　were　analyzed　by　X-ray　diffractometry　(XRD)　and　scanning　electron　microscopy　(SEM).　Three-point　flexural　strength　of　glass-ceramic　specimens　was　measured　following　the　instruction　of　ISO　6872　and　contrast　ratio　was　measured.　Different　heat-treatment　conditions　result　in　distinct　microstructure　and　properties.　As　the　temperature　increased,　the　grain　size　of　precipitated　crystals　increased.　The　highest　flexural　strength　was　recorded　for　glass-ceramic　E,　and　the　corresponding　contrast　ratio　was　0.57.　Suitable　heat-treatment　conditions　could　provide　glass-ceramic　with　superior　mechanical　properties　and　optimal　contrast　ratio,　which　may　be　considered　as　a　promising　candidate　material　for　dental　all-ceramic　application.