A　slippery　liquid-infused　porous　surface　(SLIPS)　is　able　to　improve　the　hemocompatibility　of　implantable　medical　materials,　which　have　saved　countless　lives.　However,　the　preparation　of　a　SLIPS　on　an　implantable　metal　substrate　(especially　NiTi　alloys)　is　still　a　substantial　challenge　because　of　the　great　difficulty　of　forming　abundant　porous　microstructures　on　hard　metals.　In　this　paper,　a　novel　strategy　to　prepare　a　SLIPS　on　a　NiTi　alloy　substrate　is　reported.　We　used　the　laser　pulse　train　of　a　femtosecond　Bessel　laser　rather　than　the　common　Gaussian　beam　to　directly　create　deep　porous　microstructures　on　the　surface　of　the　implantable　NiTi　alloy.　Based　on　the　laser-induced　porous　microstructure,　the　SLIPS　was　obtained　by　lowering　the　surface　energy　and　infusing　the　lubricant　liquid　into　the　pores.　The　as-prepared　SLIPS　very　effectively　repelled　water　and　blood.　The　hemocompatibility　of　the　NiTi　alloy　was　greatly　improved　after　the　formation　of　the　SLIPS　by　the　femtosecond　Bessel　laser　processing.　It　was　demonstrated　that　the　SLIPS　gives　the　NiTi　alloy　a　remarkable　anticoagulation　property,　very　low　hemolysis　rate,　and　antibacterial　property.　We　believe　that　the　laser-induced　SLIPS　will　accelerate　the　broad　application　of　metal　implants　in　the　medical　field　in　a　healthier　and　safer　way.