Background/Aims:　This　study　aimed　to　investigate　the　association　of　renalase　with　blood　pressure　(BP)　and　brachial-ankle　pulse　wave　velocity　(baPWV)　in　order　to　better　understand　the　role　of　renalase　in　the　pathogenesis　of　hypertension　and　atherosclerosis.　Methods:　A　total　of　344　subjects　with　normal　kidney　function　were　recruited　from　our　previously　established　cohort　in　Shaanxi　Province,　China.　They　were　divided　into　the　normotensive　(NT)　and　hypertensive　(HT)　groups　or　high　baPWV　and　normal　baPWV　on　the　basis　of　BP　levels　or　baPWV　measured　with　an　automatic　waveform　analyzer.　Plasma　renalase　was　determined　through　an　enzyme　linked　immunosorbent　assay.　Results:　Plasma　renalase　did　not　significantly　differ　between　HT　and　NT　groups　(3.71　+/-　0.69　mu　g/mL　vs.　3.72　+/-　0.73　mu　g/mL,　P　=　0.905)　and　between　subjects　with　and　without　high　baPWV　(3.67　+/-　0.66　mu　g/mL　vs.　3.73　+/-　0.74　mu　g/mL,　P　=　0.505).　However,　baPWV　was　significantly　higher　in　the　HT　group　than　in　the　NT　group　(1460.4　+/-　236.7　vs.　1240.7　+/-　174.5　cm/s,　P　＜　0.001).　Plasma　renalase　was　not　correlated　with　BP　levels　and　baPWV　in　the　entire　group.　Linear　and　logistic　regression　analysis　revealed　that　plasma　renalase　was　not　significantly　associated　with　hypertension　and　high　baPWV.　Conclusion:　Plasma　renalase　may　not　be　associated　with　BP　and　baPWV　in　Chinese　subjects　with　normal　renal　function.　(C)　2016　The　Author(s)　Published　by　S.　Karger　AG,　Basel