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Author:

Li, Guo-Li (Li, Guo-Li.) | Qi, Hui-Min (Qi, Hui-Min.) | He, Yi-Lin (He, Yi-Lin.) | Shen, Yu-Kai (Shen, Yu-Kai.) | Shen, Tong (Shen, Tong.)

Indexed by:

SCIE Scopus Web of Science

Abstract:

The actinomycete strain R1706-8 is isolated from a soil sample collected from the nest of the horned-face bee (Osmia cornifrons) and identified as Streptomyces sp. based upon the results of 16SrRNA sequence analysis. Two concanamycin derivatives obtained from the solid fermentation have been determined by analysis of the infrared, high-resolution electrospray ionization mass spectrometry, 1D and 2D NMR spectra as well as by comparison with literature data. Of the two derivatives, one is a new compound, named concanamycin H, and the other is the known compound, concanamycin G. These compounds are assayed for antibacterial activity, with concanamycins H and G displaying inhibitory activity against Bacillus subtilis (minimum inhibitory concentration = 0.625 mu g mL(-1)).

Keyword:

antimicrobial concanamycin Osmia cornifrons secondary metabolites Streptomyces

Author Community:

  • [ 1 ] [Li, Guo-Li]Lanzhou Jiaotong Univ, Sch Chem & Chem Engn, Anningxi Rd 188, Lanzhou 730070, Gansu, Peoples R China
  • [ 2 ] [Qi, Hui-Min]Lanzhou Jiaotong Univ, Sch Chem & Chem Engn, Anningxi Rd 188, Lanzhou 730070, Gansu, Peoples R China
  • [ 3 ] [He, Yi-Lin]Lanzhou Jiaotong Univ, Sch Chem & Chem Engn, Anningxi Rd 188, Lanzhou 730070, Gansu, Peoples R China
  • [ 4 ] [Shen, Tong]Lanzhou Jiaotong Univ, Sch Chem & Chem Engn, Anningxi Rd 188, Lanzhou 730070, Gansu, Peoples R China
  • [ 5 ] [Shen, Yu-Kai]Xi An Jiao Tong Univ, Coll Sch Marine Sci, Xian, Peoples R China

Reprint Author's Address:

  • [Shen, T.]School of Chemistry and Chemical Engineering, China;;

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Source :

JOURNAL OF CHEMICAL RESEARCH

ISSN: 1747-5198

Year: 2022

Issue: 4

Volume: 46

0 . 7 8 2

JCR@2020

ESI Discipline: CHEMISTRY;

ESI HC Threshold:6

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count: 1

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 5

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