Controlling　spin　dynamics　through　modulation　of　spin　interactions　in　a　fast,　compact,　and　energy-efficient　way　is　compelling　for　its　abundant　physical　phenomena　and　great　application　potential　in　next-generation　voltage　controllable　spintronic　devices.　In　this　work,　we　report　electric　field　manipulation　of　spin　dynamics-the　two-magnon　scattering　(TMS)　effect　in　Ni0.5Zn0.5Fe2O4　(NZFO)/Pb(Mg2/3Nb1/3)-PbTiO3　(PMN-PT)　multiferroic　heterostructures,　which　breaks　the　bottleneck　of　magnetostatic　interaction-based　magnetoelectric　(ME)　coupling　in　multiferroics.　An　alternative　approach　allowing　spin-wave　damping　to　be　controlled　by　external　electric　field　accompanied　by　a　significant　enhancement　of　the　ME　effect　has　been　demonstrated.　A　two-way　modulation　of　the　TMS　effect　with　a　large　magnetic　anisotropy　change　up　to　688　Oe　has　been　obtained,　referring　to　a　24　times　ME　effect　enhancement　at　the　TMS　critical　angle　at　room　temperature.　Furthermore,　the　anisotropic　spin-freezing　behaviors　of　NZFO　were　first　determined　via　identifying　the　spatial　magnetic　anisotropy　fluctuations.　A　large　spin-freezing　temperature　change　of　160　K　induced　by　the　external　electric　field　was　precisely　determined　by　electron　spin　resonance.