As　bimodulous　material　being　a　typical　material　with　different　elastic　moduli　in　tension　and　compression,　bimodulous　panel　aluminum　foam　core　circular　laminated　plate　is　equivalent　to　laminated　plate　composed　of　three　different　materials　under　uniform　load.　Static　equilibrium　equation　of　bimodulous　panel　aluminum　foam　core　circular　laminated　plate　under　uniform　load　is　established　using　theory　of　elasticity.　The　location　of　neutral　plane　in　bimodulous　panel　aluminum　foam　core　circular　laminated　plate　is　determined　by　the　utilization　of　static　equilibrium　equation.　The　large　deflection　bending　deformation　differential　equations　of　bimodulous　panel　aluminum　foam　core　circular　laminated　plate　are　derived,　and　relation　expression　between　central　deflection　of　circular　laminated　plate　and　uniform　load　is　obtained.　Through　the　FEM　analysis　of　circular　laminated　plate,　the　maximum　error　is　only　3.8%,　and　the　correctness　of　the　method　is　verified.　The　numerical　example　shows　that　for　the　large　bending　deflection　of　bimodulous　panel　aluminum　foam　core　circular　laminated　plate,　one　should　use　elastic　theory　with　different　elastic　moduli　in　tension　and　compression,　instead　of　with　the　same　elastic　modulus,　the　latter　would　lead　to　an　error　more　than　5%,　which　is　the　allowable　maximum　calculation　error　in　engineering.