TiO2　film　containing　20　at%　Ta　(TaTiO2　film)　was　sol-gel　coated　on　NiTi　alloy,　and　polydopamine　film　was　used　to　immobilize　arginine　molecules　onto　the　TaTiO2　film　surface　to　improve　hemocompatibility　of　NiTi　alloy.　X-ray　photoelectron　spectroscopy　analysis　indicated　that　polydopamine　film　was　formed　and　then　arginine　was　immobilized　onto　the　surface　of　TaTiO2-coated　sample.　Contact　angle　measurement　showed　that　the　polydopamine　film　and　the　arginine　molecule　layer　decreased　surface　energy　and　interface　tension　of　the　TaTiO2-coated　NiTi　sample.　The　hemocompatibility　tests　demonstrated　that　immobilization　of　arginine　molecules　improved　anti-thrombogenic　activity　and　anti-aggregating　function　of　the　TaTiO2-coated　NiTi　sample.　Copyright　(C)　2016　John　Wiley　&　Sons,　Ltd.