To　improve　the　electrical　performance　and　biocompatibility　of　the　deep　brain　stimulation　(DBS)　electrode-tissue　interface,　DC　electrophoretic　deposition　of　multi-walled　carbon　nanotubes　to　modify　electrode　is　proposed.　The　stainless　steel　plate　and　copper　electrode　are　connected　to　the　anode　and　cathode　of　DC　power　supply,　and　put　into　the　suspension　of　MWCNTs　prepared　after　purification　and　functionalization.　The　multi-walled　carbon　nanotubes　can　be　deposited　on　the　stainless　steel　plate　by　setting　voltage　and　electrophoresis　time.　The　electrophoretic　deposition　process,　stability　and　material　composition　of　multi-walled　carbon　nanotubes　film　formed　by　electrophoretic　deposition　is　investigated　and　the　biological　characters　of　modified　electrodes　are　evaluated.　The　results　show　that　the　best　combination　parameters　of　the　electrophoretic　deposition　of　multi-walled　carbon　nanotubes　are　20　V　and　7　min.　20-100　nm　carbon　nanotube　film　can　be　formed　on　the　electrode　surface　by　electrophoretic　deposition,　the　film　with　good　continuity　and　high　purity　and　without　cracks　is　endowed　with　good　biocompatibility　and　electrochemical　stability,　but　it　is　suggested　to　strengthen　the　mechanical　stability.　This　strategy　ensures　the　biocompatibility　of　electrode-tissue　interface　and　effectively　avoids　degradation　of　electrode　electrical　properties.　©　2019,　Editorial　Office　of　Journal　of　Xi＇an　Jiaotong　University.　All　right　reserved.