Heracleum　dissectum　Ledeb.　is　an　ethnic　herb　used　by　Oroqen　people　in　Northeast　China.　The　roots　of　this　plant　are　usually　used　for　treatment　of　several　diseases.　However,　chemical　constituents　and　pharmacological　study　were　rarely　reported.　In　this　present　study,　phytochemical　investigation　of　H.　dissectum　methanolic　extract　(HdME)　led　to　the　isolation　of　a　new　benzofuran　derivative　glycoside,　6-methoxycarbonylethyl-benzofuran-5-O-beta-d-xylopyranosyl　(1　-＞　2)-beta-d-glucopyranoside　(1)　and　a　new　coumarin　glycoside,　6aEuro(3)-beta-d-glucopyranosyl-apterin　(2).　Their　structures　were　elucidated　on　the　basis　of　physicochemical　properties　and　the　detailed　interpretation　of　various　spectroscopic　data.　Adipogenesis　accumulating　activity　was　assayed　in　3T3-L1　cells.　Compound　2　could　potently　accelerate　the　accumulation　of　triglycerides　(TG)　in　3T3-L1　adipocytes　in　which　TG　concentrations　were　15.6　+/-　2.3,　26.8　+/-　1.8,　and　35.6　+/-　2.6%　higher　than　those　of　the　control　group　at　the　concentration　of　3,　10,　and　30　mu　M,　respectively.　In　contrast,　compound　1　exhibited　comparatively　weak　activity　on　TG　accumulation　in　adipocytes.　This　result　denoted　that　the　new　compound　2　might　possess　antidiabetic　activity　in　vivo.